Furthermore, injection of exosomes derived from miR-125b-5p-silenced ADSCs treated with HQT-containing serum also had no significant effect on the serum levels of IL-1β (P < 0.0001), IL-6 (P < 0.01) and TNF-α (P < 0.001) of RA rat model (Fig. 7C). Here, TNF is linked to rheumatoid arthritis.