The differential expression analysis identified significant downregulation of 12 out of 20 genes (TIAM1, DCX, SNAP47, SRPX2, RAB5B, PTCH1, ATP6V0A1, NUMB, NR3C1, EIF3L, KIF3A, SDCBP) in the MDD group. The gene discussed is ATP6V0A1; the disease is major depressive disorder.