The differential expression analysis identified significant downregulation of 12 out of 20 genes (TIAM1, DCX, SNAP47, SRPX2, RAB5B, PTCH1, ATP6V0A1, NUMB, NR3C1, EIF3L, KIF3A, SDCBP) in the MDD group. This evidence concerns the gene EIF3L and major depressive disorder.