From the data we can speculate the following: 1) All myoCAF subtypes were positive for POSTN expression, suggesting a shared origin [65] and; 2) these populations may represent the cycling of different transitional cell states from early-activated tumour-proximal myoCAFs (CAF5), to more terminal differentiated myoCAFs (CAF2) to a population of less contractile and more ECM/ pro-collagen producing cells (CAF1); 3) or these cell phenotypes may represent myoCAFs residing in specific tissue niches. Here, POSTN is linked to neoplasm.