MT-ND5 and Leber hereditary optic neuropathy: Other LHON-associated LHON mutations included the ND1 3866T>C, 3635G>A, 3394T>C, ND5 12238T>C, and tRNAAla 5587T>C mutations (16, 17, 18, 19, 20, 21, 22, 23).