IL-1β mRNA is strongly induced following HCMV infection of MyD88-transduced cells (Fig. 5C), so we investigated whether IL-1β could be responsible for the blockade of HCMV spread by adding IL-1β to our monolayer of MRC-5 cells on d3 post-infection and every 3 days thereafter. The gene discussed is MYD88; the disease is infection.