MYD88 and infection: When these cells were infected with TB40/E-mCh at an MOI of 0.05 and harvested for RNA purification on d7 post-infection, a time point at which there were similar levels of virus present in cells transduced with MyD88 or the control lentivirus, this trend continued, but many additional ISGs were downregulated in the MRC-5 cells transduced with MyD88-expressing lentivirus relative to the MRC-5 cells transduced with the control lentivirus (Fig. 5B and C).