NR2F2 and cryptorchidism: More recently, defects in the external genitalia (micropenis, hypospadias) and cryptorchidism have been associated with rare heterozygous variants in NR2F2 in 46,XY patients (Zidoune et al., 2022; Ganapathi et al., 2023; Wankanit et al., 2024).