M1‐like macrophage‐derived factors, such as CXCL9 and CXCL10, are essential for the recruitment of CD8+ T cells and their production of cytotoxic mediators.[16, 17] We found that the percentages of tumor‐infiltrating CD8+ T cells were significantly higher in αPD‐L1‐treated CFD mice compared to IgG‐treated CFD mice, αPD‐L1‐treated NCD mice, and IgG‐treated NCD mice, demonstrating an obvious synergistic effect. This evidence concerns the gene CD8A and fleck corneal dystrophy.