M1‐like macrophage‐derived factors, such as CXCL9 and CXCL10, are essential for the recruitment of CD8+ T cells and their production of cytotoxic mediators.[16, 17] We found that the percentages of tumor‐infiltrating CD8+ T cells were significantly higher in αPD‐L1‐treated CFD mice compared to IgG‐treated CFD mice, αPD‐L1‐treated NCD mice, and IgG‐treated NCD mice, demonstrating an obvious synergistic effect. The gene discussed is CXCL10; the disease is neoplasm.