The peroxisome proliferator‐activated receptors (PPARs), belonging to the nuclear hormone receptor family, are ligand‐activated transcription factors with three distinct isoforms: PPARα (NR1C1), PPARβ/δ (NR1C2), and PPARγ (NR1C3), all of which exert varying degrees of influence during myocardial ischemia [33]. This evidence concerns the gene PPARA and myocardial ischemia.