Tian‐Li Yue and colleagues demonstrated that the PPARα agonist GW7647 attenuated the reduction in myocardial fatty acid oxidase activity, mitigated pro‐inflammatory cytokine release, reduced neutrophil infiltration, and suppressed NF‐κB signaling activation in a murine ischemia–reperfusion model, thereby improving cardiac contractility and reducing infarct size [34]. This evidence concerns the gene PPARA and ischemia.