Higher pre-LT alpha-fetoprotein (hazard ratio [HR]1.01; P = 0.001), poorly differentiated tumors (HR 13; P = 0.039), the presence of microvascular invasion (HR 7.9; P = 0.001), higher Total tumour volume (HR 1.03; P = 0.001), and faster tumor growth (HR 1.09; P = 0.001) were significantly associated with the risk of recurrence [45]. The gene discussed is AFP; the disease is neoplasm.