For example, the BCAP31/PINK1/Parkin pathway alleviates inflammation and oxidative stress by restoring mitochondrial autophagy in ALI (Vij, 2020; Jiang et al., 2024; Du et al., 2024), whereas downregulation of PINK1 in PF leads to impaired mitochondrial clearance and exacerbates the fibrotic process (Zhu et al., 2024). Here, PRKN is linked to acute respiratory distress syndrome.