SATB2 and colorectal carcinoma: An assessment of the methylation status of SATB2 promoter in the 28 CRC tissue samples revealed that 17 out of the 21 samples whose mRNA expression was downregulated presented a hypermethylated SATB2 promoter, whereas the remaining seven samples whose mRNA expression was upregulated presented only two samples with a hypermethylated SATB2 promoter (Table 1), indicating that the methylation status at the promoter region of SATB2 was also correlated with its mRNA expression level.