The ROC curve analysis in the total sample set revealed moderate discriminatory capacity for DUSP1 (AUC = 0.75), GADD45A (AUC = 0.72), and GADD45B (AUC = 0.70), suggesting these genes may serve as potential diagnostic biomarkers for ischemic stroke (Figure 6B). Here, GADD45B is linked to ischemic stroke.