ABCC8 and diabetes mellitus: Interestingly, ATP-binding cassettes KCNJ and ABCC8 involved in neonatal and maturity onset of diabetes and PD have been observed to be downregulated on treatment with WS deciphering the neuroprotective and antidiabetic role of WS in SK-N-SH cells (Day and Mullin, 2021; Ivanoshchuk et al., 2023).