Administration of a small-molecule inhibitor of FGFRs, which negatively regulates CILK1 activity, suppresses retinal degeneration observed in RP model Mak-deficient mice (Ozgul et al., 2011; Tucker et al., 2011; Kunova Bosakova et al., 2019; Chaya et al., 2024). Here, MAK is linked to retinitis pigmentosa 1.