Patients in the high RAR group exhibited higher heart rate, WBC, RDW, PTT, AST, lactate, total bilirubin, SOFA, APS III, SAPS II, OASIS, and SIRS scores, but lower age, red blood cell count, hemoglobin, albumin, sodium, chloride, glucose, and anion gap. The gene discussed is ALB; the disease is systemic inflammatory response syndrome.