CD8A and neoplasm: Besides the prophylactic efficiency, the formulated nanovaccine exhibited higher stability in serum and remarkably enhanced antigen delivery through internalization into immune cells, leading to strong infiltration of CD8+ T-cells within the TME and suppression of tumor growth.79 Another liposome-based, Poly(I:C) containing, and CD8+ T-cell-inducing adjuvant is CAF09 which Korsholm et al used the adjuvanticity of liposomes to design a nanovaccine.