Additionally, the production of IL-10 by DCs following immunization with rlipoE7m plus POCpG/DOTAP regimen dramatically reduced the number of tumor-infiltrating Tregs.78 To induce potent immune responses against HPV16 E7 SLPs, He et al constructed liposomal formulation incorporating cobalt–porphyrin–phospholipid (CoPoP) owing to its adjuvanticity activities. This evidence concerns the gene IL10 and neoplasm.