Among them, CPXM1 (OR: 0.53, 95% CI: 0.39 − 0.73, P < 0.001) and FLT4 (OR: 0.86, 95% CI: 0.78 − 0.95, P = 0.005) exhibited associations with glaucoma consistent with those of the corresponding proteins (Figs. 3 and 4). Here, CPXM1 is linked to glaucoma.