Gene mutations enriched in HIV+/ART-naïve compared to HIV+/ART-exp DLBCL included: BOD1L1 and EML4 (6/14 ART-naïve, 0/23 ART-exp, FDR = 0.001), IGHJ5, NCOA6, TEP1, KCNB2, (all 5/14 ART-naive, 1/23 ART-exp, FDR = 0.02), among others (Fig. 3A). This evidence concerns the gene KCNB2 and diffuse large B-cell lymphoma.