NTRK3 and pleuropulmonary blastoma: An additional report highlighted a 2-year-old child with a histologic diagnosis of initially localized PPB (no germline or somatic DICER1 variant was identified) who then had a second disease recurrence as brain metastases that demonstrated ETV6::NTRK3 fusion and was treated with larotrectinib for four cycles prior to progression of the disease and death30.