However, we identified MM cells that had no or very low IgH expression (IgG1, IgG2, IgG3, IgG4, IgA1, IgA2), these had significantly less LTK expression than MM with above average IgH expression (p = 0.0009, Mann-Whitney, Supplementary Fig. S1D). This evidence concerns the gene IGHG3 and Miyoshi myopathy.