PGD and neoplasm: High dietary D-ribulose-5p led to upregulation of released UDP levels in byn>RasG12V tumours (Fig. 2f), while knockdown of pgd significantly reduced UDP release in byn > RAP tumours (Fig. 2g); in the absence of trametinib, knockdown of pgd did not significantly reduce UDP release in byn > RAP tumours (Fig. 2h).