Additionally, animal studies have demonstrated that ginseng polysaccharides can modulate the activity of superoxide dismutase (SOD) enzymes and glutathione (GSH), significantly decrease the expression of B‐cell lymphoma‐2 (Bcl‐2) and Bax proteins in rats, and improve blood lipid profiles, thereby inhibiting the progression of atherosclerosis (Guo et al. 2021). This evidence concerns the gene SOD1 and atherosclerosis.