Apigenin, a flavonoid prevalent in temperate‐zone plants such as celery, has anti‐tumor, antiviral, antibacterial, and cardiovascular protective effects (Li, Chen, et al. 2023; Li, Mao, et al. 2023; Sain et al. 2023) Animal studies have shown that apigenin effectively inhibits NLRP3 inflammasome activation in atherosclerotic plaques, reduces ROS production, and blocks p65 nuclear translocation in the NF‐κB pathway, thereby preventing further atherosclerosis progression (Weng et al. 2023). This evidence concerns the gene NFKB1 and atherosclerosis.