CDKN1A and ovarian cancer: 2012). Genistein and daidzein (10 and 50 μM) have induced apoptosis by altering FAK and PI3K/AKT/GSK signaling pathways and p21/cyclin D1 expression in ovarian cancer cell lines. These phytoestrogens have prevented cell migration, invasion, and proliferation, and have caused cell cycle arrest (Chan et al. 2018; Swathi Krishna et al. 2022).