ACE2 was implicated in the pathogenesis of disease and in postinfectious fibrotic sequelae of COVID-19.215, 216, 217ACE2 is a membrane-bound protein that converts angiotensin I and angiotensin II to Ang-(1-9) and Ang-(1-7), respectively.218ACE2 is necessary to maintain homeostasis of PRAS. This evidence concerns the gene AGT and COVID-19.