Carbohydrates necessary to fulfill the body's energy needs are internalized inside the cell through GLUTs, transport proteins facilitating the translocation of sugars (especially glucose) and glyco‐mimetics across cell membrane.[11] To date, 14 GLUTs (GLUT1 to GLUT14) have been identified, each showing preferential affinity and recognition of specific monosaccharides.[12] Although such transporters are expressed in nearly every type of cells, most tumor cells over‐express several GLUTs (in particular GLUT1)[13] to support aerobic glycolysis and the associated increased demand for glucose. The gene discussed is SLC2A1; the disease is neoplasm.