However, dihydrolipoyl dehydrogenase (or dihydrolipoamide acetyltransferase) (DIM: log2 fold change: −2.42, fold change: −5.36; BPH: log2 fold change: −2.91, fold change: −7.51), responsible for pyruvate decarboxylation and vital for energy production in cells involved in the TCA cycle, was observed to be downregulated in both DIM and BPH. This evidence concerns the gene DLAT and benign prostatic hyperplasia.