TF and benign prostatic hyperplasia: Some proteins known to be involved in immune regulation of mosquitoes were identified after a literature review (Tables S1 and S2) [i.e., actin was significantly upregulated in both DIM (log2 fold change: 2.55, fold change: 5.84) and BPH (log2 fold change: 2.34; fold change: 5.07); prophenoloxidase was significantly upregulated in DIM (log2fold change: 1.60; fold change: 3.04) but not significantly upregulated in BPH (log2 fold change: 1.10, fold change: 2.14); In addition, insignificant downregulations of arginine kinase and transferrin were observed in both study groups.