Triosephosphate isomerase (DIM = log2 fold change: 1.89, fold change: 3.71, BPH = log2fold change: −0.13, fold change: −1.10), phosphoglycerate kinase (DIM = log2 fold change: 0.57, fold change: 1.48, BPH = log2 fold change: −1.07, fold change: −2.10) and glucose-6-phosphate isomerase (DIM = log2 fold change: 2.25, fold change: 4.75, BPH = log2 fold change: −0.75, fold change: −1.68), pyruvate kinase (DIM: log2 fold change: 0.54, fold change: 1.45; BPH: log2 fold change: −1.21; fold change: −2.32) were upregulated in DIM but downregulated in BPH. The gene discussed is GPI; the disease is benign prostatic hyperplasia.