The cumulative proportion of relative Q-TWiST gain observed in all randomized patients, patients with PD-L1 CPS ≥ 1, and patients with PD-L1 CPS ≥ 5 was greater than 88%, 92%, and 100% of the Q-TWiST gains reported in a benchmark review of all cancers at any stage, respectively [9]. Here, CD274 is linked to cancer.