To better understand the role of MPZL3 in ovarian cancer, RNA-seq was carried out following MPZL3 knockdown in OVCAR4 and OVCA433 cells, two cell lines of high-grade serous origin, using two independent shRNAs each (Fig. 2A–C; Supplementary Fig. S2A). Here, MPZL3 is linked to ovarian carcinoma.