Immunohistochemical analysis showed positive reactivity for AE1/AE3 (Figure 3B), S100 (Figure 3C), epithelial membrane antigen (EMA), CAM5.2, NSE, and Ki‐67 (< 1%) and negative reactivity for SOX10, P63, SMA, and calponin, which indicated tumors of a notochordal origin and confirmed the final diagnosis of chordoma. This evidence concerns the gene MUC1 and chordoma.