APOC1 and Alzheimer disease: A multivariate analysis revealed that the APOC1 promoter CpG site cg2327011 (which is also cpg_chr19_44914329) was differentially methylated in control and AD blood samples in the study’s replication cohort data from Gene Expression Omnibus (P = 0.019), however the significance disappeared after Holm correction for 54 CpG sites (BH-FDR corrected p value = 1.002).