For instance, premature basal ganglia mineralization, a radiographic hallmark of type I interferonopathies such as Aicardi-Goutières syndrome and stimulator of interferon genes (STING)-associated vasculopathy with onset in infancy (SAVI) and congenital infection with viruses like cytomegalovirus (CMV) (Alarcon et al., 2013; Fremond et al., 2021; La Piana et al., 2016) has been observed in several individuals with ROSAH. This evidence concerns the gene STING1 and Aicardi-Goutières syndrome.