The five glioma subpopulations were as follows: C0 CHCHD2P9+ glioma cells (2,821 cells), C1 MALT1+ glioma cells (2,124 cells), C2 MT1G+ glioma cells (1,614 cells), C3 SOX4+ glioma cells (1,575 cells), and C4 ISG15+ glioma cells (128 cells) (Figure 2A). Here, ISG15 is linked to glioma.