DAPK2 and brain ischemia: In ischemia/reperfusion injury (CI/R), DAPK2 is a direct target of miR-133a-3p and its expression is upregulated in cerebral ischemia/reperfusion injury, miR-133a-3p can attenuate CI/R injury by inhibiting the expression of DAPK2, which suggests that DAPK2 may be a potential target for the treatment of CI/R injury (Yang et al., 2023).