NQO1 and central nervous system cancer: In contrast, the expression of NQO1 in a variety of tumor cells is much higher, especially glioma, lung cancer, colon cancer and breast cancer cells, than that in normal tissues cells (Bey et al., 2007; Yang et al., 2014; Li et al., 2015; Lei et al., 2020; Jiang et al., 2024).