In addition to classic M1 and M2 gene signatures, we observed strong expression of Ccl2, a key chemokine for angiogenesis and monocyte recruitment, across CD206hi and CD206lo IMs, recMacs, and conventional dendritic cells (DCs) in tumor-bearing lungs (Fig. 4a–b)14, 35. This evidence concerns the gene CCL2 and neoplasm.