To assess their function in cancer, we used Pf4creCx3cr1DTR mice, which predominantly deplete CD206hi IMs, including those that express Cxcl13 (for B cell chemotaxis), Cxcl9 and Cxcl10 (for NK and T cell recruitment), as well as Ccl6, Ccl8, Ccl9, and Ccl2418. Here, CCL8 is linked to cancer.