CRP and infection: We hypothesized that: 1) greater genetic predisposition for elevated CRP levels is associated with an increased psychopathology risk and with altered patterns of cortical thinning; 2) genetic risk interact with early-life infection to influence the psychopathology outcomes and cortical thinning process; 3) neurobiological processes associated with cortical thinning partially mediate the relationship between genetic predisposition for high CRP levels and psychopathology.