IFNG and lymphoma: Despite great variability in the lymphoma group, the mean fold change in IFN-γ production between pre- and post-vaccination was comparable to HC, as the mean change between pre- and post-spot forming unit (SFU) per million cells in HC was 38.4-fold (p = 0.0012), and in lymphoma 37.8-fold (p = 0.0028) (Extended Fig. 3B).