Reassuringly, despite using entirely different statistical methodologies, these patterns were remarkably similar to our earlier analyses associating TNF-α with culture-positive episodes and IL-22 and CXCL10 with Gram-positive infections (Lin et al. 2013), as well as the importance of the total cell count for culture-positive episodes, IFN-γ and IL-17A for non-streptococcal Gram-positive infections, and sIL-6R for staphylococcal infections (Zhang et al. 2017). The gene discussed is IFNG; the disease is staphylococcal infection.