Qingyi decoction has been reported toregulate the STIM1/Orai1 pathway, mitigating inflammation and improving calciumhomeostasis, which could provide a promising strategy for AF treatment [156].Furthermore, enhancing the activity of the calcium ATPase SERCA2a acceleratescalcium reuptake, which not only mitigates calcium overload but also helpsrestore calcium homeostasis, offering potential therapeutic avenues for managingAF-induced electrical remodeling [157]. Here, ORAI1 is linked to atrial fibrillation.