Nup107 is increased as a fast-acting protein incardiomyocytes and rat models of infarction during hypoxia and oxidative stress,forcing an increase in the protein level of Nav1.5 in the early stages ofhypoxia, but with the prolonged duration of hypoxia existing SCN5A mRNAlibraries are depleted, and Nav1.5 expression declines [51]. This evidence concerns the gene SCN5A and infarction.