MYH9 and macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss: The preferred method of diagnosis for MHA is a genetic study for the MYH9 gene, present on chromosome 22q12-2A, due to its rarity; however, a thorough evaluation with peripheral blood smear (PBS) is recommended in those with a positive family history of bleeding diathesis.