Other BPAs, like CHE, inhibit non-small cell lung cells by downregulating β-Catenin (Heng and Cheah, 2020), while NTD suppresses epithelial mesenchymal transformation and glioma stem cells by targeting the JAK2/STAT3 signaling pathway (Jia et al., 2021). This evidence concerns the gene STAT3 and glioma.