Similarly, a single nucleotide polymorphism (SNP), rs35705950, in the promoter region of the mucin 5B (MUC5B, OMIM: 600770) gene, located 3 kb upstream of the transcription start site has been extensively reported to be associated with IPF (Seibold et al., 2011). The gene discussed is MUC5B; the disease is idiopathic pulmonary fibrosis.