Maria Latacz et al. investigated the association between the rs10877012 (T/G) polymorphism in the CYP27B1 gene and CRC susceptibility and identified a significant association between the presence of T allele and CRC incidence (OR = 2.94; 95%CI: 1.77–4.86; p < 0.0001), suggesting the impaired vitamin D metabolism might be a risk factor for CRC (Latacz et al., 2020). The gene discussed is CYP27B1; the disease is colorectal carcinoma.