Specifically, Sisi He et al. reported that high CYP27A1 expression was associated with shortened progression-free survival for ovarian cancer patients, and the expression of CYP27A1 was critical for the infiltration of monocytic myeloid derived suppressor cells to support tumor growth in an ovarian cancer mouse model (He et al., 2019). The gene discussed is CYP27A1; the disease is ovarian carcinoma.