Time from diagnosis to 1st PRRT, alkaline phosphatase, KPS, hepatomegaly, weight loss, [18F]FDG-PET scan positivity, Ki-67% derived histologic grade, lung metastases, age, presence of bone metastases, platelet count, erythrocyte count, creatinine clearance, hemoglobin, presence of functioning tumor, creatinine, and gender, were in order of importance, all independent predictors for overall survival. This evidence concerns the gene MKI67 and neoplasm.