The results revealed a significant upregulation (P < .05) in the expression levels of NOP2, NSUN2, NSUN5, NSUN5, DNMT1, DNMT3A, DNMT3B, ALYREF, MBD1, MBD2, MBD3, UHRF1, UHRF2, and TET3 in the tumor tissues. Here, DNMT3B is linked to neoplasm.