Among them, COLCA1 is considered to be involved in oxidative stress responses and serves as a biomarker for various malignant diseases such as lung cancer, gastric cancer, and colon cancer.[20,21] In RCC, COLCA1 has been identified as a biomarker for predicting early recurrence after nephrectomy and OS.[22,23] HM13-IT1 functions as an m6A-related lncRNA and acts as a biomarker for endometrial cancer.[24] There is no literature on AC010285.3 in cancer. This evidence concerns the gene COLCA1 and renal cell carcinoma.