TNF and diabetes mellitus: Following adjustment for age, sex, triglyceride levels, diabetes, and hypertension, a covariate variance analysis revealed significant differences between these groups with respect to plasma levels of TWEAK, TNF-α, IL-10, and IL-4 (PTWEAK = .017, PTNF-α < .001, PIL-10 = .010, PIL-4 = .016, Table 4).