Multiple studies have demonstrated that elevated expression of lncRNA ITSN1-2 in peripheral blood is significantly positively correlated with inflammatory responses and poor prognosis in various diseases, including sepsis [13, 15], acute ischemic stroke [12, 16], ankylosing spondylitis [17], and acute pancreatitis [18]. The gene discussed is ITSN1; the disease is ankylosing spondylitis.