miR-301a expression is correlated with tumor progression and a reduced KPS, with exosomal levels dynamically changing following tumor resection and recurrence, making it a valuable biomarker for disease monitoring.77 Additionally, exosomal miR-210, miR-5194, and miR-449 target key genes in the EGFR and cellular mesenchymal epithelial transition (c-MET) signaling pathways and are correlated with histopathological grade and GBM aggressiveness.78 Table S6 presents the miRNAs that serve as biomarkers associated with GBM pathogenesis. This evidence concerns the gene EGFR and neoplasm.