CEBPB and glioblastoma: Additionally, C/EBPβ modulates antioxidative defense mechanisms by regulating NAD(P)H quinone oxidoreductase 1 (NQO1) and glutathione S-transferase pi 1 (GSTP1), protecting GBM cells from oxidative stress.306,307 Given its multifaceted role in GBM progression, targeting C/EBPβ presents a promising therapeutic strategy.