FBXW7 and breast cancer: Unlike in other cancer types, FBW7 has a very low mutation rate in breast cancer.32 Although it has been reported that the transcription level of FBW7 in TNBC was lower than in other breast cancer subtypes, our analysis and results showed that the transcription level of FBW7 in TNBC was higher than in non-TNBC (Supplementary Fig. 6a–e).