MYC and neoplasm: Specifically, in terms of regulating c-Myc expression level in the transplanted tumor tissues, although 66CTG-3×Flag showed a tendency to upregulate c-Myc level, this effect was not as significant as 66ATG-3×Flag (Fig. 4c and Supplementary Fig. 4e), as the expression of 66CTG-3×Flag was decreased with tumor growth.